What is Fibrocell?
The procedure of reproduction of the cells, which are called fibroblasts and obtained from the skin tissue from the body, and injection of them back to the body is called fibrocell. The cells, that are reproduced and injected back to the body, are called “Fibroblast Cells”.
What are the Functions of Fibroblast Cells?
The main components of the subcutaneous connective tissue, that supports the skin and forms the skeleton of the skin, are collagen fibres. There are 19 different types of collagens in our body. Each type of collagen differs according to its location. Collagens form the raw material of tissues in the body. The collagen fibres are synthesized by fibroblast cells, that are derived from the bone marrow. In a young and healthy body, collagen fibres that are worn and aged are destroyed. Fibroblast cells synthesize new fibres in the meantime. Missing tissues are complemented by the collagen fibres formed by fibroblast cells, especially in the wounds in our body. And the wound heals.
What are the Anti-aging Effects of Fibrocell?
Fibroblast cells are produced and reproduced in the laboratory with the tissues taken from the body. The amount of reproduced cells may be at the desired rate. And it is possible to obtain an idiosyncratic and healthy fibroblast cell. These healthy and very young fibroblast cells can be transferred to the desired tissue in the body. The most important effect of this transfer is to ensure that fibroblast cells synthesize new collagen fibres, old and aged collagens in the tissue are destructed, and the amount and quality of the new collagen significantly increase. The increased amount of collagen provides many benefits to the body. With the increase in the amount of collagen, difficult and large wounds in the body quickly heals thanks to fibre synthesis, cartilage tissue is renewed in case of articular damages, and it becomes easier to support bone diseases. In addition, effects such as the revitalization of the skin on the face, in the décolleté area and hand, the increase of flexibility, and subsequent reduction of the wrinkles, that may have occurred and will occur, can be provided.
What are the Changes Occurring with Aging?
As the person ages, the cell cycle, which enables the formation of new cells instead of aged ones, slows down considerably. Similarly, as new fibroblast cells come in a small amount and late, aged fibroblast cells continue to serve, albeit slowly. Therefore, a quite apparent reduction is observed in the collagen fibre synthesis and quality. And some problems such as skin wrinkles, lifelessness, aging, bone loss, cartilage tissue erosion arise depending on the location. In particular, reduction and breakdown of the collagen fibre synthesis, loss of skin elasticity, sagging, loosening, deep wrinkles, lifelessness, and aging occur.
To whom is Fibrocell Applied?
Fibrocell stem cell therapy can be applied in patients with wounds, that are resistant to healing, and ulcers. In addition, this treatment is effective in people with severe joint degeneration. Fibrocell plays an important role in the treatment of wrinkles, that appear with aging, and skin problems in the décolleté area, face, and hand.
How is Fibrocell Applied?
Local anaesthesia is utilized in this treatment. A skin piece of 1 cm is taken from the back of the ear or the inner surface of the arm without leaving scars. This skin piece is placed in a sterile container to be transported to the laboratory. Again, an average of 4 tubes of blood is taken from the patient to be sent to the laboratory in a sterile way. In the tissue laboratory, the plasma part is separated from the blood of the patient and the medium is formed. The piece of the skin taken from the patient is placed on the formed media and the fibroblast cells are reproduced. An average of 3 weeks is required for the production of the fibroblast cell amount, that will be transferred to the patient. At the end of 3 weeks, approximately 20-40 million healthy and young fibroblast cells can be obtained. These cells are fluidized to be injected into the patient and the cell transfer to the face, top of the hand, or décolleté area of the patient is performed. This cell transfer is repeated 3 times at 3-week intervals for an effective and adequate treatment. In these repetitions, the skin sample is not taken from the patient again. The skin sample taken at the beginning of treatment is sufficient.